| We thank following people for valuable comments against S. avermitilis annotation. |
| D. Lamb | (cytochrome P450) |
| T. Nihira | (gamma-butyrolactone signaling) |
| K. Ueda | (amf genes and multi-component regulatory system) |
| M. Kitabatake | (tryptophanyl t-RNA synthetase) |
| T. Kuzuyama | (non-mevalonate pathway) |
| T. Dairi | (non-mevalonate pathway) |
| D. E. Cane | (terpene cyclase) |
| J. Sanchez | (peptidyl-prolyl cis-trans isomerase) |
| Y. Shiga | (IS and transposase) |
| J. Martin | (phosphate regulatory genes) |
| H. Shoun | (nitric oxide synthase) |
| H. Onaka | (4.5S RNA) |
| R. Brzezinski | (exo-beta-D-glucosaminidase; csxA) |
| I. Kojima | (genes for inositol metabolism) |
| S. Okamoto | (16S ribosomal RNA small subunit methyltransferase; rsmG (gidB)) |
| K. Ochi | (ppGpp synthetase; relA) |
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