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IDSAM23877_7114 TypeCDS
From7685382 nt length16344
To7701725 aa length5447
Gene pI4.92
DefinitionType I polyketide synthase M.W (Da) 568010
NoteInvolved in stambomycin biosynthesis AseI frg.
SignalP v.4.0Non-secretory protein | plot Category


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
avmSAVERM_2895 modular polyketide synthase26060.0e+00

*avm, Streptomyces avermitilis;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

ketoacyl-synt3Beta-ketoacyl synthase, N-terminal domain34-283, 2071-2320, 3610-3860840.91e-254

Acyl_transf_13Acyl transferase domain566-830, 2600-2917, 4169-4488694.71.7e-209

KR3KR domain1697-1874, 3239-3410, 5018-5197564.14.8e-171

Ketoacyl-synt_C3Beta-ketoacyl synthase, C-terminal domain291-408, 2328-2445, 3868-3985435.38.7e-133

PS-DH2Polyketide synthase dehydratase913-1189, 4539-4800354.34.5e-106

KAsynt_C_assoc3Ketoacyl-synthetase C-terminal extension411-529, 2448-2565, 3988-4134144.31.6e-42

PP-binding3Phosphopantetheine attachment site1979-2045, 3519-3585, 5302-5367139.33.5e-41

adh_short3short chain dehydrogenase1698-1856, 3239-3392, 5019-5178131.03.2e-38

Epimerase2NAD dependent epimerase/dehydratase family3240-3327, 5020-515580.98.5e-23

Thiolase_N1Thiolase, N-terminal domain172-23671.46.8e-20

Polysacc_synt_22Polysaccharide biosynthesis protein3240-3327, 5020-515269.32.6e-19

ADH_zinc_N_21Zinc-binding dehydrogenase1557-168766.73.6e-18

ADH_zinc_N1Zinc-binding dehydrogenase1527-161555.35.5e-15

RmlD_sub_bind1RmlD substrate binding domain3239-338144.11.2e-11

ADH_N1Alcohol dehydrogenase GroES-like domain1408-146431.21.4e-07

Docking1Erythronolide synthase docking2-2729.24.6e-07

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_053141458.1 type I polyketide synthase [Streptomyces ambofaciens] >gb 236670.0e+00
ANB10366.1 hypothetical protein SAM40697_6413 [Streptomyces ambofaciens] 234180.0e+00
WP_107499088.1 type I polyketide synthase [Streptomyces sp. SM14] 214890.0e+00
WP_162600233.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces sp.... 211800.0e+00
GGS45885.1 hypothetical protein GCM10010221_51160 [Streptomyces parvus] 211040.0e+00
WP_187744889.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces sp.... 185700.0e+00
WP_179230675.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces sp.... 133700.0e+00
OSC69138.1 hypothetical protein B5180_27800, partial [Streptomyces sp. BF-3] 133580.0e+00
WP_225930615.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces koy... 133130.0e+00
129370.0e+00

PSORT result

LocalizationCertaintyPSORT said
Not Clear