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IDSAVERM_2794 TypeCDS
From3427706 nt length2046
To3429751 aa length681
Genezmp3 pI8.16
Definitiongriselysin (secreted neutral zinc metalloprotease) M.W (Da)70917
NotePF02868: Thermolysin metallopeptidase, alpha-helical domain AseI frg.K
SignalP v.4.0Signal peptide | plot Categoryprotein modification


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO5447 putative neutral zinc metalloprotease9590.0e+00
sgrSGR_2095 metalloendopeptidase griselysin8940.0e+00
samSAM23877_5189 Transglutaminase-activating metalloprotease9990.0e+00
scabSCAB27921 putative neutral zinc metalloprotease9690.0e+00

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

Peptidase_M4_C1Thermolysin metallopeptidase, alpha-helical domain381-555176.24.5e-52

Peptidase_M41Thermolysin metallopeptidase, catalytic domain232-378162.77e-48

P_proprotein1Proprotein convertase P-domain600-68078.33.1e-22

FTP1Fungalysin/Thermolysin Propeptide Motif91-13650.31.5e-13

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
MYS98393.1 peptidase M4 [Streptomyces sp. SID5469] 27860.0e+00
WP_189188827.1 M4 family metallopeptidase [Streptomyces albiflavescens] >db... 24620.0e+00
WP_179332586.1 M4 family metallopeptidase [Streptomyces sp. Tue6028] >gb 24570.0e+00
WP_081219523.1 M4 family metallopeptidase [Streptomyces sp. M41(2017)] >gb 24400.0e+00
WP_164369053.1 M4 family metallopeptidase [Streptomyces sp. SID14446] >gb 24400.0e+00
WP_055493624.1 M4 family metallopeptidase [Streptomyces sp. TP-A0356] 24260.0e+00
WP_151472027.1 M4 family metallopeptidase [Streptomyces triticiradicis] >lc... 24180.0e+00
24140.0e+00
WP_187285701.1 M4 family metallopeptidase [Streptomyces sp. me109] 24130.0e+00
WP_234519889.1 M4 family metallopeptidase [Streptomyces glomeratus] >lcl 24060.0e+00

PSORT result

LocalizationCertaintyPSORT said
outside0.3000 Seems to have a cleavable N-term signal seq.