| ID | SAVERM_3510
| Type | CDS
|
| From | 4345772
| nt length | 1395
|
| To | 4344378
| aa length | 464
|
| Gene | cysM1
| pI | 4.53
|
| Definition | putative cystathionine beta-synthase
| M.W (Da) | 49048
|
| Note | PF00291: Pyridoxal-phosphate dependent enzyme
| AseI frg. | E
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of amino acids & related molecules
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO3077 putative cystathionine beta-synthase | 840 | 0.0e+00
|
| sgr | SGR_4452 putative cystathionine beta-synthase | 815 | 0.0e+00
|
| sam | SAM23877_3129 putative Cystathionine beta-synthase | 850 | 0.0e+00
|
| scab | SCAB54591 putative cystathionine beta-synthase | 877 | 0.0e+00
|
| sace | SACE_0899 cystathionine beta-synthase | 641 | 0.0e+00
|
| nfar | nfa48320 cystathionine beta-synthase | 645 | 0.0e+00
|
| mtub | gi|57116820 Probable cystathionine beta-synthase CBS (Serine sulfhydrase) (Beta-thionase) (Hemoprotein H-450) [Mycobacterium tuberculosis H37Rv] | 627 | 0.0e+00
|
| cglu | gi|19553758 COG0031:Cysteine synthase [Corynebacterium glutamicum] | 235 | 2.9e-63
|
| bsub | BG10136 cysK; cysteine synthetase A [EC:4.2.99.8] | 251 | 8.2e-68
|
| paer | PA0399 [gene=PA0399] [prot=cystathionine beta-synthase] [comment=PA0399] | 302 | 3.7e-83
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| PALP | 1 | Pyridoxal-phosphate dependent enzyme | 10-296 | 239.1 | 6.1e-71
|
| CBS | 2 | CBS domain | 340-395, 410-458 | 45.5 | 7.2e-12
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_028803882.1 | MULTISPECIES: cystathionine beta-synthase [unclassified Stre...
| 2188 | 0.0e+00 |
| WP_202498096.1 | cystathionine beta-synthase [Streptomyces sp. SID5469]
| 2185 | 0.0e+00 |
| QIY96356.1 | cystathionine beta-synthase [Streptomyces sp. S1D4-11]
| 2184 | 0.0e+00 |
| WP_101404775.1 | MULTISPECIES: cystathionine beta-synthase [Streptomyces] >gb...
| 2183 | 0.0e+00 |
| WP_168528479.1 | cystathionine beta-synthase [Streptomyces sp. RPA4-2] >gb
| 2179 | 0.0e+00 |
| WP_189192085.1 | cystathionine beta-synthase [Streptomyces albiflavescens] >d...
| 2179 | 0.0e+00 |
| WP_148008760.1 | cystathionine beta-synthase [Streptomyces sp. me109] >lcl
| 2179 | 0.0e+00 |
| WP_153290182.1 | cystathionine beta-synthase [Streptomyces fagopyri] >gb
| 2179 | 0.0e+00 |
| WP_054237278.1 | MULTISPECIES: cystathionine beta-synthase [Streptomyces] >gb...
| 2179 | 0.0e+00 |
| WP_081217687.1 | cystathionine beta-synthase [Streptomyces sp. M41(2017)] >gb...
| 2173 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| membrane | 0.1977 | Seems to have no N-terminal signal seq.
|