| ID | SAVERM_3846
| Type | CDS
|
| From | 4751640
| nt length | 882
|
| To | 4750759
| aa length | 293
|
| Gene | purU
| pI | 6.51
|
| Definition | putative formyltetrahydrofolate deformylase
| M.W (Da) | 32758
|
| Note | PF00551: Formyl transferase
| AseI frg. | G1
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of nucleotides & nucleic acids
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO4403 putative formyltetrahydrofolate deformylase (fragment) | 554 | 0.0e+00
|
| sgr | SGR_3063 putative formyltetrahydrofolate deformylase | 548 | 0.0e+00
|
| sam | SAM23877_3328 Formyltetrahydrofolate deformylase | 560 | 0.0e+00
|
| scab | SCAB51501 putative formyltetrahydrofolate deformylase | 553 | 0.0e+00
|
| sace | SACE_4502 formyltetrahydrofolate deformylase | 318 | 4.0e-110
|
| nfar | nfa52050 purU formyltetrahydrofolate deformylase | 270 | 8.4e-74
|
| mtub | gi|15610101 PROBABLE FORMYLTETRAHYDROFOLATE DEFORMYLASE PURU (FORMYL-FH(4) HYDROLASE) [Mycobacterium tuberculosis H37Rv] | 240 | 9.4e-65
|
| cglu | gi|19551628 COG0788:Formyltetrahydrofolate hydrolase [Corynebacterium glutamicum] | 263 | 5.6e-72
|
| bsub | BG13237 purU, ykkE; formyltetrahydrofolate deformylase [EC:3.5.1.10] | 265 | 3.1e-72
|
| ecoli | gi|16129193 formyltetrahydrofolate deformylase [Escherichia coli K12] | 204 | 4.3e-54
|
| paer | PA5420 [gene=purU2] [prot=formyltetrahydrofolate deformylase] [comment=PA5420] | 265 | 2.8e-72
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| Formyl_trans_N | 1 | Formyl transferase | 97-274 | 132.7 | 1.1e-38
|
| ACT_6 | 1 | ACT domain | 16-72 | 25.5 | 8.6e-06
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_126272726.1 | formyltetrahydrofolate deformylase [Streptomyces aquilus] >g...
| 1506 | 0.0e+00 |
| WP_028802804.1 | formyltetrahydrofolate deformylase [Streptomyces sp. 142MFCo...
| 1503 | 0.0e+00 |
| NUO46979.1 | formyltetrahydrofolate deformylase [Streptomyces sp.] >gb
| 1501 | 0.0e+00 |
| WP_189855817.1 | formyltetrahydrofolate deformylase [Streptomyces poonensis] ...
| 1501 | 0.0e+00 |
| WP_030673168.1 | formyltetrahydrofolate deformylase [Streptomyces cellulosae]
| 1500 | 0.0e+00 |
| WP_095935044.1 | formyltetrahydrofolate deformylase [Streptomyces sp. Tue6028...
| 1499 | 0.0e+00 |
| NUS79927.1 | formyltetrahydrofolate deformylase [Streptomyces sp.]
| 1499 | 0.0e+00 |
| WP_046259046.1 | formyltetrahydrofolate deformylase [Streptomyces sp. WM6386]...
| 1496 | 0.0e+00 |
| WP_059195925.1 | formyltetrahydrofolate deformylase [Streptomyces antibioticu...
| 1494 | 0.0e+00 |
| WP_097265528.1 | formyltetrahydrofolate deformylase [Streptomyces sp. TLI_55]...
| 1493 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.2346 | Seems to have no N-terminal signal seq.
|