| ID | SAVERM_4134
| Type | CDS
|
| From | 5073851
| nt length | 1095
|
| To | 5072757
| aa length | 364
|
| Gene | purM
| pI | 4.46
|
| Definition | putative phosphoribosylaminoimidazole synthetase
| M.W (Da) | 38185
|
| Note | PF00586: AIR synthase related protein, N-terminal domain
| AseI frg. | H
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of nucleotides & nucleic acids
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO4087 phosphoribosylformylglycinamidine cyclo-ligase | 603 | 0.0e+00
|
| sgr | SGR_3878 putative phosphoribosylaminoimidazole synthetase | 589 | 0.0e+00
|
| sam | SAM23877_3592 Phosphoribosylformylglycinamidine cyclo-ligase | 610 | 0.0e+00
|
| scab | SCAB47861 putative phosphoribosylaminoimidazole synthetase | 609 | 0.0e+00
|
| sace | SACE_7124 phosphoribosylformylglycinamidine cyclo-ligase | 446 | 3.0e-158
|
| nfar | nfa5800 purM phosphoribosylaminoimidazole synthetase | 435 | 2.6e-123
|
| mtub | gi|15607949 phosphoribosylaminoimidazole synthetase [Mycobacterium tuberculosis H37Rv] | 424 | 3.5e-120
|
| cglu | gi|19553779 COG0150:Phosphoribosylaminoimidazol (AIR) synthetase [Corynebacterium glutamicum] | 422 | 9.4e-120
|
| bsub | BG10708 purM, ath; phosphoribosylaminoimidazole synthetase [EC:6.3.3.1] | 301 | 5.2e-83
|
| ecoli | gi|16130424 phosphoribosylaminoimidazole synthetase [Escherichia coli K12] | 300 | 1.3e-82
|
| paer | PA0945 [gene=purM] [prot=phosphoribosylaminoimidazole synthetase] [comment=PA0945] | 289 | 2.4e-79
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| AIRS_C | 1 | AIR synthase related protein, C-terminal domain | 187-352 | 108.0 | 4.6e-31
|
| AIRS | 1 | AIR synthase related protein, N-terminal domain | 72-175 | 58.3 | 8.2e-16
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_168528872.1 | phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces...
| 1652 | 0.0e+00 |
| WP_148009154.1 | phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces...
| 1651 | 0.0e+00 |
| WP_071366791.1 | phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces...
| 1645 | 0.0e+00 |
| WP_055494498.1 | phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces...
| 1643 | 0.0e+00 |
| WP_153289770.1 | phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces...
| 1642 | 0.0e+00 |
| WP_190039484.1 | phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces...
| 1637 | 0.0e+00 |
| WP_151478957.1 | phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces...
| 1633 | 0.0e+00 |
| WP_189187295.1 | phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces...
| 1631 | 0.0e+00 |
| WP_189841650.1 | phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces...
| 1630 | 0.0e+00 |
| WP_055613828.1 | phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces...
| 1628 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| membrane | 0.1871 | Seems to have no N-terminal signal seq.
|