| ID | SAVERM_4139
| Type | CDS
|
| From | 5080499
| nt length | 705
|
| To | 5079795
| aa length | 234
|
| Gene | purQ
| pI | 5.58
|
| Definition | putative phosphoribosyl formylglycinamidine synthase I
| M.W (Da) | 25254
|
| Note | PF07722: Peptidase C26
| AseI frg. | H
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of nucleotides & nucleic acids
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO4078 phosphoribosyl formylglycinamidine synthase I | 421 | 1.0e-152
|
| sgr | SGR_3870 putative phosphoribosylformylglycinamidine synthetase I | 410 | 4.0e-148
|
| sam | SAM23877_3600 fragment of phosphoribosylformyl-glycineamide synthetase (part 1) | 422 | 5.0e-153
|
| scab | SCAB47801 putative phosphoribosyl formylglycinamidine synthase I | 410 | 4.0e-148
|
| sace | SACE_7143 phosphoribosylformylglycinamidine synthase I | 283 | 4.0e-98
|
| nfar | nfa5680 purQ phosphoribosylformylglycinamidine synthase I | 287 | 4.9e-79
|
| mtub | gi|15607928 phosphoribosylformylglycinamidine synthase subunit I [Mycobacterium tuberculosis H37Rv] | 277 | 3.9e-76
|
| cglu | gi|19553785 COG0047:Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain [Corynebacterium glutamicum] | 277 | 2.8e-76
|
| bsub | BG10706 purQ; phosphoribosylformylglycinamidine synthase I [EC:6.3.5.3] | 204 | 3.7e-54
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| GATase_5 | 1 | CobB/CobQ-like glutamine amidotransferase domain | 4-212 | 124.8 | 2.9e-36
|
| GATase_3 | 1 | CobB/CobQ-like glutamine amidotransferase domain | 24-96 | 38.2 | 1e-09
|
| DJ-1_PfpI | 1 | DJ-1/PfpI family | 37-103 | 33.1 | 4.1e-08
|
| GATase | 1 | Glutamine amidotransferase class-I | 35-97 | 29.3 | 6.2e-07
|
| Peptidase_C26 | 1 | Peptidase C26 | 20-94 | 23.9 | 2.7e-05
|
| SNO | 1 | SNO glutamine amidotransferase family | 18-95 | 22.8 | 6.4e-05
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_189187288.1 | phosphoribosylformylglycinamidine synthase subunit PurQ [Str...
| 1146 | 1.4e-158 |
| WP_190039479.1 | phosphoribosylformylglycinamidine synthase subunit PurQ [Str...
| 1139 | 1.9e-157 |
| WP_143627175.1 | MULTISPECIES: phosphoribosylformylglycinamidine synthase sub...
| 1135 | 8.8e-157 |
| WP_028804523.1 | phosphoribosylformylglycinamidine synthase subunit PurQ [Str...
| 1132 | 2.5e-156 |
| WP_067377082.1 | phosphoribosylformylglycinamidine synthase subunit PurQ [Str...
| 1132 | 2.7e-156 |
| WP_097285339.1 | MULTISPECIES: phosphoribosylformylglycinamidine synthase sub...
| 1130 | 3.9e-156 |
| WP_151478950.1 | phosphoribosylformylglycinamidine synthase subunit PurQ [Str...
| 1130 | 5.0e-156 |
| WP_081218205.1 | phosphoribosylformylglycinamidine synthase subunit PurQ [Str...
| 1130 | 5.1e-156 |
| WP_189776364.1 | phosphoribosylformylglycinamidine synthase subunit PurQ [Str...
| 1130 | 5.3e-156 |
| WP_095935309.1 | phosphoribosylformylglycinamidine synthase subunit PurQ [Str...
| 1129 | 5.9e-156 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.1179 | Seems to have no N-terminal signal seq.
|