| ID | SAVERM_4149
| Type | CDS
|
| From | 5092349
| nt length | 1254
|
| To | 5091096
| aa length | 417
|
| Gene | purD
| pI | 4.44
|
| Definition | putative phosphoribosylglycinamide synthetase
| M.W (Da) | 42762
|
| Note | PF01071: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
| AseI frg. | H
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of nucleotides & nucleic acids
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO4068 phosphoribosylamine-glycine ligase | 722 | 0.0e+00
|
| sgr | SGR_3859 putative phosphoribosylglycinamide synthetase | 713 | 0.0e+00
|
| sam | SAM23877_3611 Phosphoribosylamine--glycine ligase | 706 | 0.0e+00
|
| scab | SCAB47701 putative phosphoribosylglycinamide synthetase | 711 | 0.0e+00
|
| sace | SACE_7168 phosphoribosylamine--glycine ligase | 433 | 1.0e-151
|
| nfar | nfa5550 purD phosphoribosylglycinamide synthetase | 465 | 2.8e-132
|
| mtub | gi|15607912 phosphoribosylamine--glycine ligase [Mycobacterium tuberculosis H37Rv] | 451 | 3.2e-128
|
| cglu | gi|19553798 COG0151:Phosphoribosylamine-glycine ligase [Corynebacterium glutamicum] | 451 | 2.2e-128
|
| bsub | BG10711 purD; phosphoribosylglycinamide synthetase [EC:6.3.4.13] | 332 | 3.2e-92
|
| ecoli | gi|16131835 phosphoribosylamine--glycine ligase [Escherichia coli K12] | 319 | 1.9e-88
|
| paer | PA4855 [gene=purD] [prot=phosphoribosylamine--glycine ligase] [comment=PA4855] | 328 | 7.3e-91
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| GARS_A | 1 | Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain | 101-283 | 221.7 | 6.6e-66
|
| GARS_N | 1 | Phosphoribosylglycinamide synthetase, N domain | 1-100 | 111.2 | 3e-32
|
| GARS_C | 1 | Phosphoribosylglycinamide synthetase, C domain | 319-411 | 94.1 | 4.5e-27
|
| ATP-grasp | 1 | ATP-grasp domain | 113-185 | 26.0 | 5.4e-06
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_202498212.1 | phosphoribosylamine--glycine ligase [Streptomyces sp. SID546...
| 1796 | 0.0e+00 |
| WP_097265968.1 | phosphoribosylamine--glycine ligase [Streptomyces sp. TLI_55...
| 1746 | 0.0e+00 |
| OPG07116.1 | phosphoribosylamine--glycine ligase [Streptomyces sp. GKU 895]
| 1746 | 0.0e+00 |
| WP_232653368.1 | phosphoribosylamine--glycine ligase [Streptomyces sp. NR30] ...
| 1738 | 0.0e+00 |
| WP_046259677.1 | phosphoribosylamine--glycine ligase [Streptomyces sp. WM6386...
| 1737 | 0.0e+00 |
| WP_030938547.1 | phosphoribosylamine--glycine ligase [Streptomyces sp. NRRL S...
| 1736 | 0.0e+00 |
| WP_093725349.1 | phosphoribosylamine--glycine ligase [Streptomyces sp. DI166]...
| 1735 | 0.0e+00 |
| NNN38173.1 | phosphoribosylamine--glycine ligase [Streptomyces sp. S3(2020)]
| 1734 | 0.0e+00 |
|
| 1732 | 0.0e+00 |
| WP_020133964.1 | phosphoribosylamine--glycine ligase [Streptomyces sp. 351MFT...
| 1731 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| membrane | 0.1914 | Seems to have no N-terminal signal seq.
|