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IDSAVERM_418 TypeCDS
From543705 nt length10695
To533011 aa length3564
GenepteA2 pI4.68
Definitionmodular polyketide synthase M.W (Da)371263
Notefilipin gene cluster AseI frg.A
SignalP v.4.0Non-secretory protein | plot Categoryantibiotic production


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
samSAM23877_7118 modular polyketide synthase (KS-AT-DH-KR-ACP-KS-AT-DH-KR-ACP)31090.0e+00

*sam, Streptomyces ambofaciens ATCC 23877;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

ketoacyl-synt2Beta-ketoacyl synthase, N-terminal domain34-284, 1770-2020628.66.9e-190

Acyl_transf_12Acyl transferase domain585-883, 2309-2623485.11.1e-145

PS-DH2Polyketide synthase dehydratase931-1212, 2672-2942390.93.2e-117

KR2KR domain1400-1572, 3131-3303343.82e-103

Ketoacyl-synt_C2Beta-ketoacyl synthase, C-terminal domain292-409, 2028-2145304.33.5e-92

KAsynt_C_assoc2Ketoacyl-synthetase C-terminal extension412-546, 2148-2239108.22.8e-31

PP-binding2Phosphopantetheine attachment site1678-1744, 3407-347394.73e-27

adh_short2short chain dehydrogenase1401-1559, 3133-328880.88.1e-23

Thiolase_N2Thiolase, N-terminal domain181-236, 1912-197356.22.9e-15

Docking1Erythronolide synthase docking2-2744.86.1e-12

Epimerase1NAD dependent epimerase/dehydratase family1402-148642.64.3e-11

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_069925213.1 type I polyketide synthase [Streptomyces agglomeratus] >gb 139860.0e+00
WP_069931761.1 type I polyketide synthase [Streptomyces agglomeratus] >gb 139740.0e+00
WP_070343542.1 type I polyketide synthase [Streptomyces agglomeratus] >gb 139660.0e+00
WP_037687780.1 type I polyketide synthase [Streptomyces durhamensis] 135490.0e+00
WP_235490647.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces ros... 134810.0e+00
WP_191878651.1 type I polyketide synthase [Streptomyces filipinensis] >dbj 134590.0e+00
WP_120752863.1 type I polyketide synthase [Streptomyces klenkii] >gb 133850.0e+00
133460.0e+00
WP_228774864.1 type I polyketide synthase [Streptomyces sp. NRRL B-1677] 132860.0e+00
WP_086805778.1 type I polyketide synthase [Streptomyces murinus] 132070.0e+00

PSORT result

LocalizationCertaintyPSORT said
membrane0.1383 Seems to have no N-terminal signal seq.