| ID | SAVERM_4265
| Type | CDS
|
| From | 5233686
| nt length | 1806
|
| To | 5231881
| aa length | 601
|
| Gene | thiC
| pI | 5.18
|
| Definition | putative thiamine biosynthesis protein
| M.W (Da) | 66485
|
| Note | PF01964: ThiC family
| AseI frg. | H
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of coenzymes & prosthetic groups
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO3928 putative thiamine biosynthesis protein | 1121 | 0.0e+00
|
| sgr | SGR_3653 putative thiamine biosynthesis protein | 1156 | 0.0e+00
|
| sam | SAM23877_3726 thiamin (pyrimidine moiety) biosynthesis protein | 1148 | 0.0e+00
|
| scab | SCAB46341 putative thiamine biosynthesis protein | 1147 | 0.0e+00
|
| sace | SACE_0511 putative thiamine biosynthesis protein | 790 | 0.0e+00
|
| nfar | nfa53160 thiC thiamine biosynthesis protein | 785 | 0.0e+00
|
| mtub | gi|15607564 thiamine biosynthesis protein ThiC [Mycobacterium tuberculosis H37Rv] | 766 | 0.0e+00
|
| cglu | gi|19552525 COG0422:Thiamine biosynthesis protein ThiC [Corynebacterium glutamicum] | 750 | 0.0e+00
|
| bsub | BG11246 thiC, thiA; thiamin biosynthesis protein | 829 | 0.0e+00
|
| ecoli | gi|16131824 thiamine biosynthesis protein ThiC [Escherichia coli K12] | 770 | 0.0e+00
|
| paer | PA4973 [gene=thiC] [prot=thiamin biosynthesis protein ThiC] [comment=PA4973] | 774 | 0.0e+00
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| ThiC_Rad_SAM | 1 | Radical SAM ThiC family | 144-564 | 658.5 | 3.3e-198
|
| ThiC-associated | 1 | ThiC-associated domain | 34-97 | 78.5 | 2.3e-22
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| QIY72127.1 | phosphomethylpyrimidine synthase ThiC [Streptomyces sp. RLB1-33]
| 3024 | 0.0e+00 |
| QIY97012.1 | phosphomethylpyrimidine synthase ThiC [Streptomyces sp. S1D4-11]
| 3023 | 0.0e+00 |
|
| 3017 | 0.0e+00 |
| WP_030938807.1 | phosphomethylpyrimidine synthase ThiC [Streptomyces sp. NRRL...
| 3010 | 0.0e+00 |
| WP_235451710.1 | phosphomethylpyrimidine synthase ThiC [Streptomyces olivochr...
| 3009 | 0.0e+00 |
| WP_152770957.1 | phosphomethylpyrimidine synthase ThiC [Streptomyces spongiae...
| 3009 | 0.0e+00 |
| WP_142232269.1 | phosphomethylpyrimidine synthase ThiC [Streptomyces calvus] ...
| 3004 | 0.0e+00 |
| WP_161174996.1 | MULTISPECIES: phosphomethylpyrimidine synthase ThiC [Strepto...
| 3003 | 0.0e+00 |
|
| 3003 | 0.0e+00 |
|
| 3002 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.3557 | Seems to have no N-terminal signal seq.
|