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IDSAVERM_4362 TypeCDS
From5339763 nt length1146
To5340908 aa length381
GenebkdA pI4.89
Definitionputative 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4) E1-alpha chain M.W (Da)41015
NoteaceF, PF00676: Dehydrogenase E1 component AseI frg.H
SignalP v.4.0Non-secretory protein | plot Categorymain glycolytic pathways

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO3831 putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit6590.0e+00
sgrSGR_3748 putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit6120.0e+00
samSAM23877_3826 3-methyl-2-oxobutanoate dehydrogenase subunit alpha6670.0e+00
scabSCAB45311 putative 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4) E1-alpha chain6790.0e+00
saceSACE_5542 putative 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) E1-alpha chain4883.0e-174
mtubgi|15609634 PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (ALPHA SUBUNIT) PDHA (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE) [Mycobacterium tuberculosis H37Rv]2931.7e-80
bsubBG10307 bkdA1, bfmBAA, bfmB1a; branched-chain alpha-keto acid dehydrogenase E1 subunit (2-oxoisovalerate dehydrogenase alpha subunit) [EC:1.2.4.4]2015.9e-53
paerPA3417 [gene=PA3417] [prot=probable pyruvate dehydrogenase E1 component, alpha subunit] [comment=PA3417]2371.5e-63

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; mtub, Mycobacterium tuberculosis H37Rv; bsub, Bacillus subtilis; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

E1_dh1Dehydrogenase E1 component67-341246.32.9e-73

DXP_synthase_N11-deoxy-D-xylulose-5-phosphate synthase150-21229.73.2e-07

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_086784881.1 pyruvate dehydrogenase (acetyl-transferring) E1 component su... 15500.0e+00
WP_192332707.1 pyruvate dehydrogenase (acetyl-transferring) E1 component su... 15450.0e+00
WP_045558550.1 MULTISPECIES: pyruvate dehydrogenase (acetyl-transferring) E... 15420.0e+00
WP_168529119.1 pyruvate dehydrogenase (acetyl-transferring) E1 component su... 15420.0e+00
WP_086800942.1 pyruvate dehydrogenase (acetyl-transferring) E1 component su... 15400.0e+00
QIY97125.1 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit... 15400.0e+00
WP_067384794.1 pyruvate dehydrogenase (acetyl-transferring) E1 component su... 15380.0e+00
WP_054234201.1 MULTISPECIES: pyruvate dehydrogenase (acetyl-transferring) E... 15380.0e+00
WP_143602322.1 MULTISPECIES: pyruvate dehydrogenase (acetyl-transferring) E... 15380.0e+00
WP_097285480.1 pyruvate dehydrogenase (acetyl-transferring) E1 component su... 15380.0e+00

PSORT result

LocalizationCertaintyPSORT said
Not Clear Seems to have no N-terminal signal seq.