| ID | SAVERM_4592
| Type | CDS
|
| From | 5606872
| nt length | 675
|
| To | 5606198
| aa length | 224
|
| Gene |
| pI | 6.05
|
| Definition | putative transcriptional regulator with cyclic nucleotide-binding domain
| M.W (Da) | 24526
|
| Note | PF00027: Cyclic nucleotide-binding domain
| AseI frg. | L
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | regulation
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO3571 putative transcriptional regulator | 422 | 4.0e-153
|
| sgr | SGR_3333 putative Crp/Fnr-family transcriptional regulator | 432 | 3.0e-157
|
| sam | SAM23877_4091 cAMP receptor protein | 422 | 4.0e-153
|
| scab | SCAB41311 putative transcriptional regulator with cyclic nucleotide-binding domain | 431 | 8.0e-157
|
| sace | SACE_0329 transcriptional regulator, Crp/Fnr family | 238 | 7.0e-81
|
| nfar | nfa3460 transcriptional regulator | 275 | 3.1e-75
|
| mtub | gi|15610812 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY CRP/FNR-FAMILY) [Mycobacterium tuberculosis H37Rv] | 265 | 2.5e-72
|
| cglu | gi|19551541 COG0664:cAMP-binding domains - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Corynebacterium glutamicum] | 250 | 4.4e-68
|
| bsub | BG11343 fnr; transcriptional regulator of anaerobic genes (FNR family) | 85 | 2.4e-18
|
| ecoli | gi|16131236 cyclic AMP receptor protein [Escherichia coli K12] | 98 | 4.0e-22
|
| paer | PA0652 [gene=vfr] [prot=transcriptional regulator Vfr] [comment=PA0652] | 86 | 2.1e-18
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| cNMP_binding | 1 | Cyclic nucleotide-binding domain | 29-110 | 91.1 | 3.1e-26
|
| HTH_Crp_2 | 1 | Crp-like helix-turn-helix domain | 148-221 | 61.8 | 4e-17
|
| Crp | 1 | Bacterial regulatory proteins, crp family | 175-199 | 22.6 | 5.7e-05
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_014046869.1 | MULTISPECIES: Crp/Fnr family transcriptional regulator [Stre...
| 1032 | 2.6e-141 |
| WP_010473292.1 | MULTISPECIES: Crp/Fnr family transcriptional regulator [Stre...
| 1031 | 3.7e-141 |
| WP_123460131.1 | MULTISPECIES: Crp/Fnr family transcriptional regulator [uncl...
| 1030 | 4.9e-141 |
| WP_148840632.1 | Crp/Fnr family transcriptional regulator [Streptomyces sp. s...
| 1028 | 1.2e-140 |
| WP_185033934.1 | MULTISPECIES: Crp/Fnr family transcriptional regulator [Stre...
| 1028 | 1.2e-140 |
| MZD08422.1 | cyclic nucleotide-binding domain-containing protein [Streptomyces...
| 1027 | 1.2e-140 |
| WP_031090867.1 | MULTISPECIES: Crp/Fnr family transcriptional regulator [Stre...
| 1027 | 1.2e-140 |
| WP_006382668.1 | MULTISPECIES: Crp/Fnr family transcriptional regulator [Stre...
| 1027 | 1.3e-140 |
| WP_007264960.1 | MULTISPECIES: Crp/Fnr family transcriptional regulator [uncl...
| 1027 | 1.4e-140 |
| WP_156693126.1 | Crp/Fnr family transcriptional regulator [Streptomyces ficel...
| 1027 | 1.4e-140 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.1446 | Seems to have no N-terminal signal seq.
|