| ID | SAVERM_5064
| Type | CDS
|
| From | 6137249
| nt length | 2079
|
| To | 6139327
| aa length | 692
|
| Gene | mtrB
| pI | 10.71
|
| Definition | putative two-component system sensor kinase
| M.W (Da) | 73162
|
| Note | probably essential TCR, PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
| AseI frg. | B
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | sensors
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO3012 putative two-component system histidine kinase | 1025 | 0.0e+00
|
| sgr | SGR_4524 putative two-component system sensor kinase | 811 | 0.0e+00
|
| sam | SAM23877_3050 Sensor histidine kinase MtrB | 1011 | 0.0e+00
|
| scab | SCAB55291 putative two-component system sensor kinase | 1028 | 0.0e+00
|
| sace | SACE_6446 sensory transduction histidine kinase | 434 | 2.0e-145
|
| nfar | nfa46100 two-component system sensor kinase | 433 | 2.1e-122
|
| mtub | gi|15610381 TWO COMPONENT SENSORY TRANSDUCTION HISTIDINE KINASE MTRB [Mycobacterium tuberculosis H37Rv] | 449 | 2.2e-127
|
| cglu | gi|19551982 COG0642:Signal transduction histidine kinase [Corynebacterium glutamicum] | 331 | 7.9e-92
|
| ecoli | gi|16131751 two-component sensor protein [Escherichia coli K12] | 127 | 3.2e-30
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; ecoli, Escherichia coli K-12;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| HATPase_c | 1 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | 462-571 | 70.0 | 2.1e-19
|
| HisKA | 1 | His Kinase A (phospho-acceptor) domain | 348-415 | 51.4 | 7.4e-14
|
| HAMP | 1 | HAMP domain | 288-336 | 30.5 | 3.5e-07
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_103841144.1 | MtrAB system histidine kinase MtrB [Streptomyces sp. Ru72] >...
| 2476 | 0.0e+00 |
| WP_189184660.1 | MtrAB system histidine kinase MtrB [Streptomyces albiflavesc...
| 2472 | 0.0e+00 |
| WP_055495153.1 | MtrAB system histidine kinase MtrB [Streptomyces sp. TP-A035...
| 2446 | 0.0e+00 |
| WP_200417735.1 | MtrAB system histidine kinase MtrB [Streptomyces sp. Y2F8-2]...
| 2425 | 0.0e+00 |
| WP_071368753.1 | MtrAB system histidine kinase MtrB [Streptomyces colonosanan...
| 2389 | 0.0e+00 |
| WP_161243313.1 | MtrAB system histidine kinase MtrB [Streptomyces sp. SID2888...
| 2384 | 0.0e+00 |
| WP_151484344.1 | MtrAB system histidine kinase MtrB [Streptomyces albicerus]
| 2374 | 0.0e+00 |
| WP_059127764.1 | MULTISPECIES: MtrAB system histidine kinase MtrB [unclassifi...
| 2352 | 0.0e+00 |
| WP_234517094.1 | MtrAB system histidine kinase MtrB [Streptomyces glomeratus]...
| 2346 | 0.0e+00 |
| WP_211117990.1 | MtrAB system histidine kinase MtrB [Streptomyces sp. RPA4-2]
| 2335 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| membrane | 0.5310 | Seems to have no N-terminal signal seq.
|