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IDSAVERM_6904 TypeCDS
From8237732 nt length1290
To8239021 aa length429
GeneribA1 pI4.98
Definitionputative GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase (dhbp synthase) M.W (Da)46388
NotePF00926: 3,4-dihydroxy-2-butanone 4-phosphate synthase AseI frg.G2
SignalP v.4.0Non-secretory protein | plot Categorymetabolism of coenzymes & prosthetic groups


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO1441 3,4-dihydroxy-2-butanone 4-phosphate synthase7630.0e+00
sgrSGR_6092 "putative GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase"7320.0e+00
samSAM23877_1502 Riboflavin biosynthesis protein RibBA7640.0e+00
scabSCAB75621 putative GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase (dhbp synthase)7650.0e+00
saceSACE_2123 3,4-dihydroxy-2-butanone 4-phosphate synthase4943.0e-175
nfarnfa36000 ribBA 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II5222.0e-149
mtubgi|15608553 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium tuberculosis H37Rv]4846.0e-138
cglugi|19552807 COG0108:3,4-dihydroxy-2-butanone 4-phosphate synthase [Corynebacterium glutamicum]4837.1e-138
bsubBG10520 ribA; GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase (dhbp synthase) [EC:3.5.4.25]4244.9e-120
ecoligi|16130937 3,4-dihydroxy-2-butanone 4-phosphate synthase [Escherichia coli K12]2023.5e-53
paerPA4054 [gene=ribB] [prot=GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase] [comment=PA4054]2657.8e-72

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

DHBP_synthase13,4-dihydroxy-2-butanone 4-phosphate synthase22-215279.88.2e-84

GTP_cyclohydro21GTP cyclohydrolase II225-390236.11.3e-70

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_055492920.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/G... 18920.0e+00
WP_234516909.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/G... 18760.0e+00
WP_055517739.1 MULTISPECIES: bifunctional 3,4-dihydroxy-2-butanone-4-phosph... 18620.0e+00
WP_099500278.1 MULTISPECIES: bifunctional 3,4-dihydroxy-2-butanone-4-phosph... 18540.0e+00
WP_210581350.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/G... 18440.0e+00
WP_099923815.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/G... 18400.0e+00
WP_168489993.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/G... 18390.0e+00
WP_189146170.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/G... 18360.0e+00
WP_200708874.1 MULTISPECIES: bifunctional 3,4-dihydroxy-2-butanone-4-phosph... 18320.0e+00
WP_165257681.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/G... 18320.0e+00

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.0010 Seems to have no N-terminal signal seq.