| ID | SAVERM_6952
| Type | CDS
|
| From | 8297249
| nt length | 627
|
| To | 8296623
| aa length | 208
|
| Gene | blaB4
| pI | 5.2
|
| Definition | putative metallo-beta-lactamase
| M.W (Da) | 22017
|
| Note | PF00753: Metallo-beta-lactamase superfamily
| AseI frg. | T
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | detoxification
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO0740 putative hydrolase | 213 | 3.0e-71
|
| sgr | SGR_5825 putative hydrolase | 226 | 3.0e-76
|
| sam | SAM23877_6787 putative hydrolase | 214 | 1.0e-71
|
| scab | SCAB6881 putative metallo-beta-lactamase | 251 | 5.0e-86
|
| sace | SACE_4442 probable hydroxyacylglutathione hydrolase | 248 | 5.0e-85
|
| nfar | nfa12220 hypothetical protein | 247 | 6.1e-67
|
| mtub | gi|15609397 hypothetical protein Rv2260 [Mycobacterium tuberculosis H37Rv] | 228 | 3.0e-61
|
| cglu | gi|19551570 COG0491:Zn-dependent hydrolases, including glyoxylases [Corynebacterium glutamicum] | 212 | 1.2e-56
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| Lactamase_B | 1 | Metallo-beta-lactamase superfamily | 29-192 | 63.6 | 2.3e-17
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| NGO09607.1 | MBL fold metallo-hydrolase [Streptomyces scabichelini]
| 924 | 2.5e-125 |
| WP_030613406.1 | MBL fold metallo-hydrolase [Streptomyces fulvoviolaceus]
| 904 | 2.4e-122 |
| WP_124443875.1 | MBL fold metallo-hydrolase [Streptomyces sp. NL15-2K] >dbj
| 898 | 1.6e-121 |
| WP_079102614.1 | MBL fold metallo-hydrolase [Streptomyces sp. TP-A0356]
| 896 | 4.1e-121 |
| WP_217566287.1 | MBL fold metallo-hydrolase [Streptomyces sp. GbtcB7]
| 880 | 1.4e-118 |
| WP_030644875.1 | MULTISPECIES: MBL fold metallo-hydrolase [Streptomyces]
| 879 | 1.5e-118 |
| WP_095855869.1 | MULTISPECIES: MBL fold metallo-hydrolase [unclassified Strep...
| 879 | 2.2e-118 |
| WP_067366266.1 | MBL fold metallo-hydrolase [Streptomyces olivochromogenes] >...
| 878 | 2.7e-118 |
| WP_031024976.1 | MBL fold metallo-hydrolase [Streptomyces sp. NRRL WC-3725]
| 875 | 6.0e-118 |
| WP_210592037.1 | MBL fold metallo-hydrolase [Streptomyces sp. GESEQ-35]
| 873 | 1.1e-117 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.1775 | Seems to have no N-terminal signal seq.
|