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IDSAVERM_955 TypeCDS
From1214909 nt length1764
To1216672 aa length587
GenepoxB1 pI5.04
Definitionputative pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors M.W (Da)62373
NotePF02776: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain AseI frg.A
SignalP v.4.0Non-secretory protein | plot Categorymain glycolytic pathways


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
scabSCAB17191 putative pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors3063.0e-97
nfarnfa1510 poxB pyruvate oxidase3026.1e-83
bsubBG12063 ydaP; pyruvate oxidase [EC:1.2.3.3]3549.0e-99

*scab, Streptomyces scabies 87.22; nfar, Nocardia farcinica IFM 10152; bsub, Bacillus subtilis;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

TPP_enzyme_N1Thiamine pyrophosphate enzyme, N-terminal TPP binding domain4-169178.86.3e-53

TPP_enzyme_C1Thiamine pyrophosphate enzyme, C-terminal TPP binding domain402-548130.34.6e-38

TPP_enzyme_M1Thiamine pyrophosphate enzyme, central domain190-31996.69.6e-28

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_202497674.1 thiamine pyrophosphate-dependent enzyme [Streptomyces sp. SI... 27480.0e+00
WP_189135492.1 thiamine pyrophosphate-dependent enzyme [Streptomyces tyrosi... 25930.0e+00
WP_230652324.1 thiamine pyrophosphate-dependent enzyme [Streptacidiphilus s... 25920.0e+00
WP_171394911.1 thiamine pyrophosphate-dependent enzyme [Streptomyces asoens... 25260.0e+00
WP_020127284.1 thiamine pyrophosphate-dependent enzyme [Streptomyces sp. 30... 25250.0e+00
WP_230196037.1 thiamine pyrophosphate-dependent enzyme [Streptomyces sp. CM... 25230.0e+00
WP_142268489.1 thiamine pyrophosphate-dependent enzyme [Streptomyces sp. SL... 25210.0e+00
WP_057604580.1 thiamine pyrophosphate-dependent enzyme [Streptomyces sp. Ro... 25150.0e+00
WP_069773442.1 thiamine pyrophosphate-dependent enzyme [Streptomyces sp. LU... 25100.0e+00
WP_007379379.1 MULTISPECIES: thiamine pyrophosphate-dependent enzyme [Strep... 24960.0e+00

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.0460 Seems to have no N-terminal signal seq.