If no values are given then the optimal default values are used ! (shown below)
The D-cutoff score is a combined value from both Signal-peptide and cleavage site prediction networks. A score above the a specified threshold (see below), will result in a positive prediction of a signal peptide. By default the following values are used for the SignalP-noTM and SignalP-TM networks for the organism types: Eukaryotes (euk), Gram-positive bacteria (gram+) and Gram-negative bacteria (gram-).
euk | SignalP-noTM networks: | 0.45 |
euk | SignalP-TM networks: | 0.50 |
gram+ | SignalP-noTM networks: | 0.57 |
gram+ | SignalP-TM networks: | 0.45 |
gram- | SignalP-noTM networks: | 0.57 |
gram- | SignalP-TM networks: | 0.51 |